GENETICS 302
page 2

Course #: 34-BIOL-302-001

SYLLABUS
David B. Fankhauser, Ph.D.

Office: Room E215P

Winter Quarter
Professor of Biol & Chem

Hours: 12-1, M-F

2000-2001
U.C. Clermont College

http://www.clc.uc.edu/~fankhadb Batavia OH 45103



COURSE OBJECTIVES FOR GENETICS 244: To learn these aspects of Genetics:

1) history of its understanding

2) Mendelian analysis and its power

3) chromosomal inheritance & mapping

4) mutations: their induction &effects

5) recombination

6) DNA structure and replication

7) transcription and translation

8) regulation of gene expression

9) modern genetics research techniques

10) social implications of genetics

11) nomenclature & etymology of genetics

REQUIRED TEXT: Griffiths, A.J.F., J.H. Miller, David T. Suzuki, R.C. Lewontin, W.M Gelbart,

An Introduction to Genetic Analysis, 7th Ed., W.H. Freeman and Co, (2000).

REQUIRED MATERIALS FOR LAB: (Meets Tuesdays, 1:00 to 4:00)

Graph-lined Comp Notebook & Black waterproof fine-tipped pen: Pilot Precise Rolling Ball (V5 or V7)

OPTIONAL RESOURCE TEXT:

Borror, Donald J., Dictionary of Word Roots and Comb'ng Forms, Mayfield Pub., (1960).

Please fasten this calendar inside the front cover of your text and bring the text to class daily.

Homework is due on the date in which the page and problem numbers appear in bold.

MONDAY
WEDNESDAY
FRIDAY


[Quizzes: Tuesdays, 1:00]		 1/3
Introduction to Genetics:

Milestones in its understanding

1-5, 28-37, 67-76, 242-245

 1/5
Mendelian Analysis

Elements of Probability

37-47

1/8 Chromosomes: Hereditary units

Mitosis and Meiosis

[QUIZ I, 1/9] 67-99

 1/10 Constructing pedigrees

Sex Linkage 56:2,6a,15,20a

40-53

 1/12
Sex Linkage, concluded

63:35,36,41,42,45

1/15

Martin Luther King Day

(No classes)
 1/17
Allelic forms,

Modified Mendelian Ratios

102:24,28,32 105-124

 1/19
Chromosome

Linkage and Mapping

130:7,15,24(1+2),28 141-149

1/22 Three point test crosses



[QUIZ II, 1/23] 150-153

 1/24
Discuss quiz

2 test

166:7,8,20,33 124-127

 1/26
Mutant types:

Selectn & Inductn

168:22,27a&b,29 463-488

1/29
Changes in Chromosome

Structure & Number

523-576 [NBS DUE 1/30]

 1/31 Recomb'n: bacteria & phage

491:3,10,12;578:1 207-233

 2/2
Deoxyribonucleic Acid:

History of its understanding

NBs back 235:1,2,3,17 241-253

2/5

MIDTERM
 2/7

Midterm returned and discussed
 2/9
DNA:

Chemical Structure

3-5, 243-248

2/12
Mechanism of Replication



249-263

 2/14
What is a gene?

Genetic Fine Structure

267-290

2/16
DNA Function I:

Transcription

292:7,14,25 299-306

2/19
Eukaryotic RNA

and its processing

[QUIZ III, 2/20] 306-312

 2/21
DNA Function II:

Translation

312-330

 2/23
Manipulation of DNA I:

Restriction Enzymes

365-370

2/26
Manipulation of DNA II:

Cloning and selecting genes

370-384

 2/28 Manipulation of DNA III:

Sequencing & "Fingerprinting"

384-394, 439-445

 3/2
Gene Regulation I:

The lac operon, a classic example

396:7,11 335-343

3/4 Gene Regul'n II: exmpls&mechs

363:1,2 344-361

QUIZ IV TODAY [NB DUE 3/5]

 3/6
Mutagenesis



495-510

 3/8
Repair Mechanisms



Notebooks back 510-519

3/12
FINAL EXAM

No clue... maybe:

1:30-3:30, Tuesday 3/12?

Assigned readings and homework (in bold) are to be complete prior to class on the indicated date. Grades are determined by your position on a histogram of student cumulative points (tests, quizzes, homework and lab notebooks). Midline generally marks the middle of the Bs. See How To Take A Fankhauser Sophomore Course for additional info. 8 Jan 01